Malignant Pleural Mesothelioma An Update
Category : Health » Mesothelioma Disease
With new treatments based on better understand . Surgical treatment alone for mesothelioma has been . in the treatment of human mesothelioma tumors in .
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Mesothelioma Disease
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xposure to asbestos is the most frequent, but notexclusive, cause of malignant mesothelioma. Clinicalfeatures include dyspnea, cough, nonspecific chestpain, weight loss and night sweats. Diagnosis may becomplicated by histologic difficulties. Thoracoscopictechniques are proving beneficial, but no one methodof imaging has proven superior, and disease staging isinconsistent. Conventional treatments such aschemotherapy, surgery, and radiotherapy have hadvariable impacts, although chemotherapy is useful inpalliation and can improve both survival and quality oflife. There is hope for new antimetabolite agents. Therole of radical surgery is yet to be evaluated in a largetrial. New radiotherapeutic techniques to improve localcontrol are promising. Multimodality treatmentsappear to be the most successful for management ofpotentially resectable disease. It is likely that biologicalmarkers will improve accuracy in staging and progno-sis. With new treatments based on better understand-ing of the biology of the disease, there is cautious opti-mism for the future for patients with malignant pleuralmesothelioma. Key words: neoplasm; mesothelioma;epidemiology; diagnosis; chemotherapy; surgery;radiotherapy; novel therapies.
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